A 28-gene panel covering inherited clotting and bleeding disorders. Includes the common thrombophilia variants (Factor V Leiden in F5, prothrombin in F2), the protein C/S/antithrombin pathway, von Willebrand factor, and the hemophilia A/B factor genes.
Clinical areas covered
- —Factor V Leiden and prothrombin variants
- —Protein C / protein S deficiency
- —Antithrombin deficiency
- —Von Willebrand disease
- —Hemophilia A and B
- —Platelet-function disorders
Analyzed genes -- 28 genesShow all genes →Hide genes ↑
- ADAMTS13
- F10
- F11
- F12
- F13A1
- F13B
- F2
- F5
- F7
- F8
- F9
- GFI1B
- GP1BA
- GP1BB
- GP6
- GP9
- HRG
- ITGA2B
- ITGB3
- LMAN1
- MCFD2
- NBEAL2
- PROC
- PROS1
- SERPINC1
- SERPIND1
- SERPINF2
- VWF
Limitations
- !F8 intronic inversions are not detected by the standard short-read sequencing assay -- if hemophilia A is clinically suspected, an inversion-specific test is required.
Gene list version 2026-05.