27-gene panel for adult-onset inherited metabolic disorders.
A 27-gene panel for adult-onset inherited metabolic disorders — late-presenting lysosomal, mitochondrial, and metabolic conditions that often go undiagnosed for years.
This is a predictive genetic test.
The order page will ask you to either book counseling or waive counseling in writing per German GenDG §10. Your choice is fully documented and accessible at any time.
Order in three clicks, no login. Kit ships from Berlin within 5 working days.
Follow the guided sample collection. Your AI-interpreted clinical report arrives by secure email.
Discuss findings with your physician or our medical geneticist; retest as your interventions evolve.
Do you carry inherited variants for metabolic disorders that present in adulthood, including late-onset Pompe, Fabry, Gaucher, X-ALD, MLD, and alpha-1 antitrypsin deficiency?
Atlas analyzes each gene in its entirety -- not just hotspot regions -- against current clinical literature. Findings are reviewed by a board-certified medical geneticist before release.
A 27-gene panel for inherited metabolic disorders that can first present in adulthood. Many of these conditions are typically associated with childhood disease but have late-onset forms that go undiagnosed for years -- adult-onset Pompe, Fabry, Gaucher, X-linked adrenoleukodystrophy.
Gene list per CeGaT PRV12 (2026-05).
Several of these disorders have specific enzyme-replacement or substrate-reduction therapies (Pompe, Fabry, Gaucher, MPS-I). Late diagnosis often means irreversible organ damage that earlier treatment could have prevented. Alpha-1 antitrypsin deficiency, for instance, accelerates emphysema and liver disease and is heavily underdiagnosed.
Every Atlas predictive report uses the same five-outcome framework so you and your physician can read it the same way each time.
Increased disease risk. The report includes an individualized prevention plan and a recommendation to discuss next steps with a physician or medical geneticist.
Probable disease association. Preventive monitoring is typically justified; the strength of evidence is documented in the report.
Reported but not currently actionable. A VUS may be reclassified over time as new evidence accumulates -- Atlas does not act on VUS findings without specialist review.
No pathogenic or likely-pathogenic variant was identified in the analyzed genes. This does not eliminate all genetic risk -- only the genes in this panel were assessed.
When an actionable variant is found, cascade testing of first-degree relatives is typically recommended -- a decision made together with a counselor.
Predictive genetic testing in Germany requires consultation with a physician qualified in human genetics under §7 of the GenDG (Arztvorbehalt). Atlas Counseling provides this before and after the test. When an actionable finding has implications for relatives, your counselor will discuss cascade testing -- not Atlas alone.
A variant indicates predisposition. It does not confirm a condition is currently present.
Imaging, lab work, and physical examination remain part of clinical care. Atlas results inform them; they do not substitute for them.
Environment, behavior, age, and chance contribute to most common conditions. A genetic test reads one input.
Only the genes on the panel were analyzed. Variants in other genes, in non-coding regions, and outside the assay's technical scope are not assessed.
Atlas reports are designed to be reviewed with a physician or medical geneticist. We do not recommend acting on a finding without that conversation.
GenDG §7
Predictive panels on this page are GenDG §7 Arztvorbehalt: counseling with a qualified human-genetics physician is required before and after the test. Atlas Counseling is included in the order flow.
Ready to start? €390 · 3–4 weeks after sample arrival
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